A Case Report of Naloxone in Poisoning with Opium

Introduction: Naloxone, sold under the brand name Nar can among others, is a medication used to block the effects of opioids, especially in overdose.

Case Presentation: The patient is a 49-year-old woman who came to Hirmand Hospital because of oral poisoning. The patient has come forward with complaints of shortness of breath. The symptoms at the onset of an emergency include hypertension 43.4, body temperature 36, pulse 54, respiratory rate 30, and GCS 13. The actions taken included ECG, CBC, CPK-LDH, NWK-Troponins-BMR-urine tests It has been reported that normal EKG and white blood cell count have been reported in 18.7%, and protein excretion has been seen in the urine, and a crackle has been heard in the lungs of the lungs, which has been given due to the symptoms of pneumonia. The patient received an emergency dose of 50% dextrose serum, saline 500 CC, 6 Naloxone 0.6 mg antibiotic, gastric nasal tube and Foley catheter. For the patient, 30 Naloxone capsules of 0.4 mg with 1 liter of dextrose saline were prescribed. For 8 hours, the patient received sodium bicarbonate 7.5% vial for treatment. CKMB fell to 35 from the first day of 1950. CPK changes from 62050 to 117. 

Conclusion: Since the patient has a history of heart attacks and pneumonia, the use of Naloxone in the first place is associated with a reduction in symptoms. The use of bicarbonate also has an effect on blood purification, especially since the person has acidosis after taking opium. 

Keywords: Naloxone, opium, poisoning.